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STUDIES ON ANTIBACTERIAL ACTIVITY OF Adenium obesum (Apocynaceae) STEM-BARK


Author: Tijjani .A, I .G. Ndukwe and R.G.Ayo
Keywords: KEYWORDS: Gram Negative; bacterial studies; Stem-bark; Adenium obesum
Collection: opensource

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¬¬ ABSTRACT

Antibacterial evaluation of the methanolic and petroleum spirit (60-80) oC extracts of the stem-bark of adenium obesum was carried out using agar- well diffusion method. The extracts were tested against some selected standard gram negative bacteria strainsâEscherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC- 25619), Salmonella typhi(ATCC 9184), Neisseria gonorrhea (NCTC 8198), Klebsiella pneumonia(ATCC 15380). Antimicrobial sensitivity test of the extracts at concentration of 4Ã104 µg/á´m3 showed significant zones of inhibition against 80% of the tested organisms. The minimum inhibitory concentration (MIC) of the extracts against the listed organisms ranges from 1Ã104 µg/á´m3 to 4Ã104 µg/á´m3 and 3Ã104 µg/á´m3 to 5Ã104 µg/á´m3 for Crude extracts of the methanol and petroleum spirit respectively. Phytochemical examination of the extracts revealed the presence of alkaloids, steroids, saponins, glycosides, anthraquinones, tannins and flavonoids. These findings reveal broad spectrum activity of the plant stem-bark extracts.


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Mediatype: texts
Identifier: StudiesOnAntibacterialActivityOfAdeniumObesumapocynaceaeStem-bark
Identifier-access: http://www.archive.org/details/StudiesOnAntibacterialActivityOfAdeniumObesumapocynaceaeStem-bark
Identifier-ark: ark:/13960/t6m04zr5d
Ppi: 300
Ocr: ABBYY FineReader 8.0

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